“Fitness Meets Niche Construction and Symbiosis”, Institute of Philosophy, Jagiellonian University, Kraków 2019

 

 

The term  fitness is used very often in evolutionary biology and plays a central role in  the  theory of evolution. However,  for  decades , the status of this concept has been debated , and  many questions have been raised by  philosophers and biologists alike . What is the definition  of fitness? What does being fitter really mean, in scientific terms ? How  can fitness be  measured ? In  recent years , new ideas  have  emerged within the scientific community  which  might shed some new light on our understanding of fitness. However, their  relationship to  the  debate concerning fitness still need s to be established.  Two things , among many others,  are  particularly  worth mentioning here : first , the theory of niche construction ,  which invites us to  think of  an  environment  not  as  being  granted  to  organisms , but  as  created by them . Thus this  theory  transforms our understanding of environments, a concept which  figures  frequently  in  fitness literature. Second , microbiology teaches us that plants and animals interact with many  symbiotic microorganisms.  Moreover,  these  microbes exert  a  major impact on  the fitness of  these plants and animals ,  thus expanding our knowledge of the factors that determine  fitness. The question is  whether – and  if so,  how – these discoveries influence the debate concerning  fitness. The aim of the workshop is  to  explore this question.

Keynote Speaker:

Lynn Chiu is a philosopher of biology  affiliated with the ImmunoConcept Lab of  the  University of Bordeaux/CNRS , which operates  at the intersection of  biology and philosophy.  Her past research and current interest s concern many important problems  found at the frontiers of  the  philosophy of biology,  such as  the  philosophy of perception, niche  construction,  symbiosis , and biological individuality.  Learn more about Lynn here : https://sites.google.com/view/lynnchiu/

Program (click to enlargen)

 

General Information

Organizers: Institute of Philosophy, Jagiellonian University
Coordinator: Adrian Stencel

Who can apply?

Philosophers, biologists, medical doctors, and any other scholars, at any point in their career,  who are interested in this subject .

Where  and  when  will  the workshop  be held ?

In  Kraków,  6th and 7th of  June 2019 .

How to apply?

Send  an  abstract (max imum 500 words) before 31 March 2019 to:  philbio.workshops@gmail.com
All decision s will be made  prior to 30 April  2019 .

 

This workshop is supported by

 

The epigenetics of inflammaging, new review by Nadini et al.

 
A growing amount of evidences indicates that inflammaging – the chronic, low grade inflammation state characteristic of the elderly – is the result of genetic as well as environmental or stochastic factors.
In their latest review Christine Nadini, Jean-François Moreau, Noémie Gensous, Francesco Ravaioli, Paolo Garagnani and Maria Giulia Bacalini take a closer look how age related epigenetic changes promote inflammaging. Furthermore they discuss the role on envioronmental and microbial stimuli and how they can affect the rate of inflammaging via epigenetic mechanisms.
Find the full article here.

Trends in Cancer: what is the tumor environment?

 
If and how a tumor develops, depends in large part on its surroundings. While scientists agree on the importance of the tumor environment (TE), there is no consensus on how to define and spatially delineate it.
A new paper by Lucie Laplane, Dorothée Duluc, Nicolas Larmonier, Thomas Pradeu and Andreas Bikfalvi lays out six clearly defined layers that surround the tumor: (i) the tumor cell-only environment, (ii) the niche, and the (iii) confined, (iv) proximal, (v) peripheral, and (vi) organismal tumor environment. The authors show the different tumor-promoting or -suppressing mechanisms at work in the different layers and how they impact therapeutic approaches.

 
Click here for more information: The Multiple Layers of the Tumor Environment
Click here for the PDF

Thomas Pradeu on the microbiome at the College de France

On June 29th 2018, Thomas Pradeu gave a talk on “Microbiome: The Second Immune System” at the Collège de France, invited by Philippe Sansonetti (Chair in Microbiology and Infectious Diseases) at the Symposium “Microbiome and Human Evolution: (Micro)Biology Meets Anthropology
The talk builds on collective work, published in: Chiu L., Bazin T. (co-first authors), Truchetet M-E., Schaeverbeke T., Delhaes L. & Pradeu T. (2017), Protective Microbiota: From Localized to Long-Reaching Co-Immunity. Frontiers in Immunology, Volume 8, Article 1678. (Open Access).
Video:

 
Video download