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Uri Alon (Weizmann Institute of Science, Israel), Simplifying inflammation and fibrosis
24 May 2023 | 14 h 00 min - 15 h 30 min
Uri Alon is Professor, Department of Molecular Cell Biology, Weizmann Institute, Israel. His lab studies biological circuits using a combined experimental and theoretical approach, aiming to uncover general underlying principles that govern their functioning and evolution.
Video of the talk:
Abstract:
Fibrosis -excess scarring- is a condition that cuts across medicine, causes many diseases, and has no cure. It is a complex process with many cell types and molecules. We will show how a minimal mathematical model can form concepts that explain the basic features of fibrosis. These concepts led to experiments that provide new drug candidates that reduce fibrosis in mice for heart attacks and liver fibrosis. No knowledge of either fibrosis or math is needed to understand this talk.